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	<title>Critical Insight</title>
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	<link>http://criticalinsight.wordpress.com</link>
	<description>A 24/7 journal club from intensivists in the East Midlands</description>
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		<title>Critical Insight</title>
		<link>http://criticalinsight.wordpress.com</link>
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		<item>
		<title>A Black Water Day ?</title>
		<link>http://criticalinsight.wordpress.com/2011/05/28/a-black-water-day/</link>
		<comments>http://criticalinsight.wordpress.com/2011/05/28/a-black-water-day/#comments</comments>
		<pubDate>Sat, 28 May 2011 11:29:26 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[CVS]]></category>
		<category><![CDATA[Physiology]]></category>
		<category><![CDATA[sepsis]]></category>
		<category><![CDATA[2011]]></category>
		<category><![CDATA[fluid]]></category>
		<category><![CDATA[NEJM]]></category>
		<category><![CDATA[Peadatrics]]></category>

		<guid isPermaLink="false">https://criticalinsight.wordpress.com/2011/05/28/a-black-water-day/</guid>
		<description><![CDATA[Mortality after Fluid Bolus in African Children with Severe Infection. Maitland, K et al. New England Journal of Medicine, May 26th 2011 (epub ahead of print) (DOI: 10.1056/NEJMe1105490) An interesting paper published in this weeks NEJM will cause substantial comment and concern after it’s headline result showed increased mortality with rapid fluid resuscitation in paediatric [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=192&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
		<wfw:commentRss>http://criticalinsight.wordpress.com/2011/05/28/a-black-water-day/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>The Pinocchio Effect</title>
		<link>http://criticalinsight.wordpress.com/2011/01/21/the-pinocchio-effect/</link>
		<comments>http://criticalinsight.wordpress.com/2011/01/21/the-pinocchio-effect/#comments</comments>
		<pubDate>Fri, 21 Jan 2011 10:06:36 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Reviews]]></category>
		<category><![CDATA[2010]]></category>
		<category><![CDATA[Anaesethesia]]></category>
		<category><![CDATA[Research methods]]></category>

		<guid isPermaLink="false">https://criticalinsight.wordpress.com/2011/01/21/the-pinocchio-effect/</guid>
		<description><![CDATA[An interesting editorial published a couple of months ago in Anaesthesia by Neil Soni. It adds to the growing disquiet that our understanding of disease, and attempts to find effective remedies, are being hampered by the tendency to treat all organ failures equally. I agree that there seems little reason to believe that meningococal sepsis [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=190&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
		<wfw:commentRss>http://criticalinsight.wordpress.com/2011/01/21/the-pinocchio-effect/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>NMB in Early ARDS.</title>
		<link>http://criticalinsight.wordpress.com/2010/11/25/nmb-in-early-ards/</link>
		<comments>http://criticalinsight.wordpress.com/2010/11/25/nmb-in-early-ards/#comments</comments>
		<pubDate>Thu, 25 Nov 2010 21:52:19 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[RS]]></category>
		<category><![CDATA[2010]]></category>
		<category><![CDATA[ARDS]]></category>
		<category><![CDATA[NEJM]]></category>
		<category><![CDATA[NMB]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/?p=186</guid>
		<description><![CDATA[A fascinating study from the NEJM. Neuromuscular Blockers in Early ARDS. Papazian, L et al. NEJM. Vol 6, 12, 2010. This RCT gave a 48 hr infusion of cis-atricurium to early (&#60;24hrs) ARDS patients. It is the first study to show a mortality difference in this condition since ARDSnet a decade ago (although caution is [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=186&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>6</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>Oxygen &#8211; too much of a good thing ?</title>
		<link>http://criticalinsight.wordpress.com/2010/08/30/oxygen-too-much-of-a-good-thing/</link>
		<comments>http://criticalinsight.wordpress.com/2010/08/30/oxygen-too-much-of-a-good-thing/#comments</comments>
		<pubDate>Mon, 30 Aug 2010 13:47:04 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[2010]]></category>
		<category><![CDATA[CPR]]></category>
		<category><![CDATA[JAMA]]></category>
		<category><![CDATA[Oxygen]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/?p=174</guid>
		<description><![CDATA[We&#8217;ve known for sometime that high inspired oxygen fractions (&#62;0.8) are associated with atelechasis (and decruitment / shunt) and lung injury and suspected that hyperoxia also leads to the generation of toxic oxygen free radicals, which may have deleterious effects in other pathologies. A recent paper adds to this story; Association between arterial hypoxia following [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=174&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>0</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>Post Publication Peer Review</title>
		<link>http://criticalinsight.wordpress.com/2010/08/23/post-publication-peer-review/</link>
		<comments>http://criticalinsight.wordpress.com/2010/08/23/post-publication-peer-review/#comments</comments>
		<pubDate>Mon, 23 Aug 2010 14:57:52 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Links - EBM]]></category>
		<category><![CDATA[Reviews]]></category>
		<category><![CDATA[Technology]]></category>

		<guid isPermaLink="false">https://criticalinsight.wordpress.com/?p=179</guid>
		<description><![CDATA[First an apology, there&#8217;s been quite a gap since my last post. I will be trying my best to increase the frequency of appraisals on Critical Insight, especially since Schringer &#38; Altman&#8217;s editorial in this week&#8217;s BMJ. They comment that the &#8220;lack of post-publication review of medical research is a sign of an unhealthy research [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=179&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>2</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>SOAP II &#8211; That&#8217;s cleaned that up then.</title>
		<link>http://criticalinsight.wordpress.com/2010/03/15/soap-ii-thats-cleaned-that-up-then/</link>
		<comments>http://criticalinsight.wordpress.com/2010/03/15/soap-ii-thats-cleaned-that-up-then/#comments</comments>
		<pubDate>Mon, 15 Mar 2010 10:28:54 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[CVS]]></category>
		<category><![CDATA[Physiology]]></category>
		<category><![CDATA[sepsis]]></category>
		<category><![CDATA[2010]]></category>
		<category><![CDATA[NEJM]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/2010/03/15/soap-ii-thats-cleaned-that-up-then/</guid>
		<description><![CDATA[Dopamine has been the vasopressor of choice in septic patients in continental europe historically, although this may be changing. Dopamine has theoretically beneficial effects in maintaining splancnic and renal perfusion although in the SOAP trial (observational) suggested that there was an excess of mortality of dopamine treated patients. The old story of “renal dose dopamine” [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=171&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>0</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>BIS &#8211; magic prediction post arrest ?</title>
		<link>http://criticalinsight.wordpress.com/2010/02/01/bis-magic-prediction-post-arrest/</link>
		<comments>http://criticalinsight.wordpress.com/2010/02/01/bis-magic-prediction-post-arrest/#comments</comments>
		<pubDate>Mon, 01 Feb 2010 15:44:28 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Neuro]]></category>
		<category><![CDATA[Technology]]></category>
		<category><![CDATA[2010]]></category>
		<category><![CDATA[ICM]]></category>
		<category><![CDATA[monitors]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/2010/02/01/bis-magic-prediction-post-arrest/</guid>
		<description><![CDATA[A fascinating paper very well reviewed by Dr. James Dawson at the QMC journal club; The bispectral index and suppression ratio are very early predictors of neurological outcome during therapeutic hypothermia after cardiac arrest Intensive Care Med. 2010 Feb;36(2):281-8. Epub 2009 Oct 22. There is a pdf version of Dr. Dawson’s presentation in the blue [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=168&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
		<wfw:commentRss>http://criticalinsight.wordpress.com/2010/02/01/bis-magic-prediction-post-arrest/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>Renal Intensity &#8211; How High ?</title>
		<link>http://criticalinsight.wordpress.com/2010/01/24/renal-intensity-how-high/</link>
		<comments>http://criticalinsight.wordpress.com/2010/01/24/renal-intensity-how-high/#comments</comments>
		<pubDate>Sun, 24 Jan 2010 21:29:47 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Renal]]></category>
		<category><![CDATA[2009]]></category>
		<category><![CDATA[CVVH]]></category>
		<category><![CDATA[ICM]]></category>
		<category><![CDATA[NEJM]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/2010/01/24/renal-intensity-how-high/</guid>
		<description><![CDATA[The ANZICS group appear to have done it again; that is taken a single centre trial done in Europe, repeated it in a sensible and pragmatic way but in a much larger, adequately powered multi centre setting and determined an evidence based outcome. It’s something of a shame that again the evidence based outcome doesn’t [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=165&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>0</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>Medpedia &amp; Twitter</title>
		<link>http://criticalinsight.wordpress.com/2009/11/18/medpedia-twitter/</link>
		<comments>http://criticalinsight.wordpress.com/2009/11/18/medpedia-twitter/#comments</comments>
		<pubDate>Wed, 18 Nov 2009 11:49:53 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Technology]]></category>
		<category><![CDATA[Medpedia]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/?p=152</guid>
		<description><![CDATA[Critical Insight has been included as a founding member of Medpedia&#8217;s News &#38; Analysis website. Medpedia is an exciting project to build a first class medical resource on the internet using world wide wiki collaboration in association with major US universities, you can find more details here. Critical Insight was started to try and encourage [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=152&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>0</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
		</media:content>
	</item>
		<item>
		<title>Special K &#8211; time for a reappraisal ?</title>
		<link>http://criticalinsight.wordpress.com/2009/09/14/special-k-time-for-a-reappraisal/</link>
		<comments>http://criticalinsight.wordpress.com/2009/09/14/special-k-time-for-a-reappraisal/#comments</comments>
		<pubDate>Mon, 14 Sep 2009 05:00:45 +0000</pubDate>
		<dc:creator>danharvey</dc:creator>
				<category><![CDATA[Anaesthesia]]></category>
		<category><![CDATA[Neuro]]></category>
		<category><![CDATA[sepsis]]></category>
		<category><![CDATA[induction]]></category>
		<category><![CDATA[ketamine]]></category>
		<category><![CDATA[TBI]]></category>

		<guid isPermaLink="false">http://criticalinsight.wordpress.com/?p=144</guid>
		<description><![CDATA[2 recent articles highlight the potential benefit of an often overlooked induction agent in critically ill patients. Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Jabre, P. et al. Lancet. Volume 374, Issue 9686, Pages 293 &#8211; 300, 25 July 2009. This multicentre, randomised, blinded trial in 65 [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=criticalinsight.wordpress.com&amp;blog=3978585&amp;post=144&amp;subd=criticalinsight&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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		<slash:comments>0</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">dan harvey</media:title>
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