Early vs delayed administration of norepinephrine in patients with septic shock. Bai et al. Critical Care 2014, 18:532
Appraisal by Dr. Peter Tsim. Read more »
The following discussion is taken from a presentation given at JC by Dr Dave Hewson, ST5 Anaesthetics, in which he explores the utility of PROCALCITONIN: Read more »
Effect of prone positioning during mechanical ventilation on mortality among patients with acute respiratory distress syndrome: a systematic review and meta-analysis
Appraiser: Dr Andrew Langton Read more »
The effect of a multicomponent multidisciplinary bundle of interventions on sleep and delirium in medical and surgical intensive care patients.
Patel J, Baldwin J, Bunting P, Laha S
Anaesthesia. 2014 Jun;69(6):540-9
Role of troponin in patients with chronic kidney disease and suspected acute coronary syndrome: a systematic review.
Sylvie R. Stacy, et al
Ann Intern Med. Published online 12 August 2014 doi:10.7326/M14-0746 Read more »
Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial.
Morelli A1 et al
JAMA. 2013 Oct 23;310(16):1683-91. doi: 10.1001/jama.2013.278477.
STUDY APPRAISER: Dr David Smith Read more »
Non-invasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial.
Lower Tidal Volume Strategy (3ml/kg) Combined with Extracorporeal CO2 Removal Versus ‘Conventional’ Protective Ventilation (6 ml/kg) in Severe ARDS (Bein et al)
QMC AICU Journal Club, April 2013.
Dr Amit Pancholi
Here’s a taster of the excellent stuff available over at sthjournalclub. Go & follow this blog now!
Myburgh JA, Finfer S, Bellomo R et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. New England Journal of Medicine 2012; 367: 1901-1911.
RHH Journal Club. November 22nd, 2012. Dr Balaji Kasa
No free full-text available
To evaluate the safety and efficacy of 6% HES (130/0.4) in 0.9% saline as compared to 0.9% saline alone for fluid resuscitation in ICU.
Type of Study: Multicentre, Prospective, Blinded, Parallel group, Randomised controlled trial
7000 patients from 32 hospitals in Australia and New Zealand, 18 years or older eligible for admission to ICU and who met the criteria for fluid resuscitation
Exclusions: more than 1000mls of HES is administered to patient before screening, those with impending or current dialysis dependent renal failure and those with intracranial haemorrhage on CT scan.
HES(130/0.4) in 0.9% saline or 0.9% saline
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