Early NA in sepsis

Early vs delayed administration of norepinephrine in patients with septic shock. Bai et al. Critical Care 2014, 18:532

Appraisal by Dr. Peter Tsim.  Read more »

Procalcitonin – D Dimer for sepsis?

The following discussion is taken from a presentation given at JC by Dr Dave Hewson, ST5 Anaesthetics, in which he explores the utility of PROCALCITONIN: Read more »

Proning – Is it worth the hassle?

Effect of prone positioning during mechanical ventilation on mortality among patients with acute respiratory distress syndrome: a systematic review and meta-analysis

Appraiser: Dr Andrew Langton Read more »

Sleep like a baby?

The effect of a multicomponent multidisciplinary bundle of interventions on sleep and delirium in medical and surgical intensive care patients.
Patel J, Baldwin J, Bunting P, Laha S
Anaesthesia. 2014 Jun;69(6):540-9

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Trop tops?

Role of troponin in patients with chronic kidney disease and suspected acute coronary syndrome: a systematic review.

Sylvie R. Stacy, et al

Ann Intern Med. Published online 12 August 2014 doi:10.7326/M14-0746 Read more »

Esmolol in septic shock

Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial.

Morelli A1 et al

JAMA. 2013 Oct 23;310(16):1683-91. doi: 10.1001/jama.2013.278477.

STUDY APPRAISER: Dr David Smith Read more »

Hear no Evil?

The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients

Van Rompaey et al. Critical Care 2012, 16:R73. (full text available)

 

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Extubation to NIPPV

Non-invasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial.

Ornico SR, Lobo SM, Sanches HS, Deberaldini M, Tófoli LT, Vidal AM, Schettino GP, Amato MB, Carvalho CR, Barbas CS. Crit Care. 2013 Mar 4;17(2):R39. (full text available)

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Xtravent

Lower Tidal Volume Strategy (3ml/kg) Combined with Extracorporeal CO2 Removal Versus ‘Conventional’ Protective Ventilation (6 ml/kg) in Severe ARDS (Bein et al)

Intensive Care Med Vol 39, Issue 5, pg 847–856, May 2013

QMC AICU Journal Club, April 2013.

Dr Amit Pancholi 

 

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Salt is better than sugar

danharvey:

Here’s a taster of the excellent stuff available over at sthjournalclub. Go & follow this blog now!

Originally posted on STH Journal Club:

Myburgh JA, Finfer S, Bellomo R et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. New England Journal of Medicine 2012; 367: 1901-1911.

RHH Journal Club. November 22nd, 2012. Dr Balaji Kasa

No free full-text available

To evaluate the safety and efficacy of 6% HES (130/0.4) in 0.9% saline as compared to 0.9% saline alone for fluid resuscitation in ICU.

Type of Study: Multicentre, Prospective, Blinded, Parallel group, Randomised controlled trial

Methodology:

Population:

7000 patients from 32 hospitals in Australia and New Zealand, 18 years or older eligible for admission to ICU and who met the criteria for fluid resuscitation

Exclusions: more than 1000mls of HES is administered to patient before screening, those with impending or current dialysis dependent renal failure and those with intracranial haemorrhage on CT scan.

Intervention /Control

HES(130/0.4) in 0.9% saline or 0.9% saline

Outcomes

Primary-…

View original 115 more words

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